Academic Papers
1. Luo L., Ando S., Sakamoto Y., Suzuki T., Takahashi H., Ishibashi N., Kojima S., Kurihara D., Higashiyama T., Yamamoto K., *Matsunaga S., *Machida C., *Sasabe M., *Machida Y., (2019) The formation of perinucleolar bodies is important for normal leaf development and requires the zinc-finger DNA-binding motif in Arabidopsis ASYMMETRIC LEAVES2, Plant J. 101(5):1118-1134 (2020) (DOI: 10.1111/tpj.14579) [PubMed]
2. Vial-Pradel S., Hasegawa Y., Nakagawa A., Miyaki S., Machida Y., Kojima S., *Machida C., *Takahashi H., (2019) SIMON: Simple methods for analyzing DNA methylation by targeted bisulfite next-generation sequencing, Plant Biotechnol. 36(4): 213-222 (2019) (DOI: 10.5511/plantbiotechnology.19.0822a)
3. Vial-Pradel S., Keta S., Nomoto M., Luo L., Takahashi H., Suzuki M., Yokoyama Y., Sasabe M., Kojima S., Tada Y., Machida Y., Machida C. (2018) Arabidopsis zinc-finger-like protein ASYMMETRIC LEAVES2 (AS2) and two nucleolar proteins maintain gene body DNA methylation in the leaf polarity gene ETTIN (ARF3). Plant Cell Physiol 1385-1397
4. Luong Q. T., Keta S., Asai T., Kojima S., Nakagawa A., Micol J. L., Xia S., Machida Y. and Machida C. (2018) A genetic link between epigenetic repressor AS1-AS2 and DNA replication factors in establishment of adaxial-abaxial leaf polarity of Arabidopsis Plant Biotechnology 35, 39–49 DOI:10.5511/plantbiotechnology.18.0129b
5. Matsumura Y., Ohbayashi I., Takahashi H., Kojima S., Ishibashi N., Keta S., Nakagawa A., Hayashi R., Saez-Vasquez J., Echeverria M., Sugiyama M., Nakamura K., Machida C. and Machida Y. (2016) A genetic link between epigenetic repressor AS1-AS2 and a putative small subunit processome in leaf polarity establishment of Arabidopsis Biol. Open, 5, 942-954. DOI:10.1242/bio.019109
6. Machida C., Nakagawa A., Kojima S. and Machida Y. (2015) The complex of ASYMMETRIC LEAVES (AS) proteins plays a central role in antagonistic interactions of genes for leaf polarity specification in Arabidopsis WIREs Developmental Biology 4(6), 655-671 DOI: 10.1002/wdev.196
7. Machida C., Nakagawa A., Kojima S., Takahashi H., and Machida Y. The complex of ASYMMETRIC LEAVES (AS) proteins plays a central role in antagonistic interactions of genes for leaf polarity specification in Arabidopsis. WIREs Developmental Biology 4, 655-671 (2015)
8. Iwasaki M., Takahashi H., Iwakawa H., Nakagawa A., Ishikawa T., Tanaka h., Matsumura Y., Pekker I., Eshed Y., Vial-Pradel S., Ito T., Watanabe Y., Ueno Y., Fukazawa H., Kojima S., Machida Y. and Machida C. Dual regulation of ETTIN (ARF3) gene expression by AS1-AS2, which maintains the DNA methylation level, is involved in stabilization of leaf adaxial-abaxial partitioning in Arabidopsis. Development 140, 1958-1969 (2013)
9. Takahashi H., Iwakawa H., Ishibashi N., Iwasaki, M., Kojima, S., Matsumura Y., Prananingrum, P., Takahashi, A., Ikezaki, M., Luo, L., Kobayashi, T., Machida, Y. and Machida, C. Meta-analyses of microarrays of Arabidopsis asymmetric leaves2 (as2) and as1 mutants reveal a critical role of the ETT pathway in stabilization of adaxial-abaxial patterning and cell division during leaf development. Plant Cell Physiol 54, 418-431 (2013)
10. Takahashi H., Nakagawa A., Kojima S., Takahashi A., Cha B. Y., Woo J., Nagai K., Machida Y. and Machida C. Discovery of novel rules for G-quadruplex-forming sequences in plants by using bioinformatics methods. J. Bioscience and Bioengineering 114, 570-575 (2012)
11. Nakagawa A., Takahashi H., Kojima S., Sato N., Ohga K., Cha B. Y., Woo J., Nagai K., Horiguchi G., Tsukaya H., Machida Y. and Machida C. Berberine enhances defects in the establishment of leaf polarity in asymmetric leaves1 and asymmetric leaves2 of Arabidopsis thaliana. Plant Molecular Biology 79, 569-581 (2012)
12. Keta S., Iwakawa I., Ikezaki M., Semiarti E., Kojima S., Machida Y. and Machida C. Roles of the ASYMMETRIC LEAVES2 gene in floral organ development in Arabidopsis thaliana. Plant Biotechnology 29, 1-8 (2012)
13. Ishibashi N., Kanamaru K., Ueno Y., Kojima S., Kobayashi T., Machida C. and Machida Y. ASYMMETRIC-LEAVES2 and an ortholog of eukaryotic NudC domain proteins repress expression of AUXIN-RESPONSE-FACTOR and class 1 KNOX homeobox genes for development of flat symmetric leaves in Arabidopsis. Biology Open 1, 197-207 (2012)
14. Kojima S., Iwasaki M., Takahashi H., Imai T., Matsumura Y., Fleury D., Van Lijsebettens M., Machida Y. and Machida C. ASYMMETRIC LEAVES2 and Elongator, a Histone Acetyltransferase Complex, Mediate the Establishment of Polarity in Leaves of Arabidopsis thaliana. Plant Cell Physiol. 52(8), 1259-1273 (2011)
Symposium, Presentation
1. Ando S., Ogawa T., Kojima S., Sakamoto Y., Matsunaga S., Machida Y., and Machida C. Roles of perinucleolar AS2 bodies and the nucleolus in the establishment of leaf polarity in Arabidopsis thaliana. Plant Organ Growth Sympojium 2019（POGS2019） 24-26, April, 2019 (Bordeaux, France)
2. Machida C., Vial-Pradel S., Nomoto M., Takahashi H., Kojima S., Tada Y.and Machida Y.Roles of Nucleolar Proteins and Zinc-Finger Protein ASYMMETRIC LEAVES2 in the establishment of leaf adaxial-abaxial polarity in Arabidopsis thaliana. Plant Organ Growth Sympojium 2019（POGS2019） 24-26, April, 2019 (Bordeaux,France)
3. Vial-Pradel S. Nomoto M., Takahashi H., Ando S., Suzuki M., Kojima S., Tada Y., Machida Y., Machida C. Arabidopsis zinc-finger-like protein ASYMMETRIC LEAVES2 (AS2) bound exon 1 of ETTIN (ARF3) and maintain gene body DNA methylation in ETTIN together with nucleolar proteins EMBO workshop New shores in land plant evolution 20-22, June, 2018 (Lisbon, Portugal)
4. Vial-Pradel S., Keta S., Nakagawa A., Suzuki M., Matsumura Y., Kojima S., Machida Y. and Machida C. (2017) Genetic and molecular interactions between nucleolar factors and AS1-AS2 for regulation of ETT/ARF3 expression in establishment of leaf polarity in Arabidopsis thaliana. Bilateral Closure Symposium of GDRI Integrative Plant Biology Network, France Lyon, October 23-25
5. Nakagawa A., Takahashi H., Kojima S., Machida Y., Machida C.Chemical genetic analyses infer that AS1-AS2 protects developing leaves from camptothecin influence by repressing ARF3 andKRP5.Mechanisms in Plant Development. August 2-7, 2015 (Saxtons River, Vermont, USA)
6. Nakagawa A., Takahashi H., Ito T., Kojima S., Machida Y., Machida C. Chemical genetic analyses infer that AS1-AS2 controls cell division through ETTIN in leaf adaxial-abaxial and medio-lateral patterning. The 25th International Conference on Arabidopsis Research (ICAR2014). July 28 – August 1, 2014 (University of British Columbia Vancouver, Canada).
7. Takahashi H., Nakagawa A., Ishibashi N., Kojima S., Machida Y., Machida C. Knowledge-based bioinformatic analyses of microarrays predict that epigenetic regulator AS1-AS2 controls cell division through ETTIN in leaf adaxial-abaxial patterning. The 25th International Conference on Arabidopsis Research (ICAR2014). July 28 – August 1, 2014 (University of British Columbia Vancouver, Canada).
8. Kojima S., Takahashi H., Ishibashi N., Handayani A., Matsumura Y., Machida Y., Machida C. ASYMMETRIC LEAVES1 (AS1) and AS2 regulate the expression of AtIPT3 through AUXIN RESPONSE FACTOR3/ETTIN function during leaf development in Arabidopsis thaliana. International Symposium 2014 on Auxins and Cytokinins in Plant Development. June 29 – July 4, 2014 (Prague, Czech Republic)
9. Ishibashi N., Kojima S., Kojima M., Sakakibara H., Takahashi H., Machida C. Machida Y. AS2 and BOB1 synergistically regulate cytokinin levels and the establishment of leaf adaxial-abaxial polarity through the ETT/ARF3-IPT3 pathway in Arabidopsis thaliana. International Symposium 2014 on Auxins and Cytokinins in Plant Development. June 29 – July 4, 2014 (Prague, Czech Republic)
10. Kojima S., Takahashi H., Ishibashi N., Handayani A., Matsumura Y., Prananingrum P., Machida Y. and Machida C. Federation of American Societies for Experimental Biology Science Research Conference Mechanisms in Plant Development. The 2013 FASEB Science Research Conferences (SRC). Mechanisms in Plant Development. August 11-16, 2013 (Vermont Academy)
11. Machida Y., Iwasaki M., Takahashi H., Nakagawa A., Kojima S., Matsumura Y., Ishibashi N., Luo L., PrananingrumP., Takahashi M., Minami A., Sasabe M., Eshed Y. and Machida C. ASYMMETRIC LEAVES2 (AS2)/AS1 is a developmental stabilizer for the leaf formation in Arabidopsis. 4th NIBB-MPIPZ-TLL Symposium “Arabidopsis and Emerging Model Systems”. November, 2012 (Okazaki)
12. Nakagawa A., Takahashi H., Kojima S., Sato N., Ohga K., Cha B. Y., Woo J., Nagai K., Horiguchi G., Tsukaya H., Machida Y. and Machida C. Berberine enhances defects in the establishment of leaf adaxial-abaxial polarity in asymmetric leaves1 and asymmetric leaves2 of Arabidopsis thaliana. 23rd International Conference on Arabidopsis Research (ICAR2012). July, 2012 (Vienna)